I'm having the same issue but with a different graphics system. I have been running R9 on my Microsoft Surface Pro 4 for years. I recently purchased a new Surface Pro 9 and installed RealFlight and now I'm having the same issue with all the menus grayed out and the controller does nothing with the plane sitting on the runway. Everything is fully up to date and I'm running a 12th gen Intel I7 processor and Intel Iris XE graphics. R9 worked fine out of the box on my old Surface, so not sure what is the difference. I also upgraded to the latest version of 9.5. I did a compatibility check of my system for R9 and it said it met the requirements. Maybe RealFlight doesn't work with the latest hardware out there? Any help would be much appreciated.
If you are running the Steam version you could try the dxvk-intel-fix beta, to get the beta, right click on RF9 name in your library, select "Properties", select "Betas" and select "dxvk-intel-fix" from the list, (see picture attached).
Unfortunately, RF9 does not work good with integrated Intel graphics adapter on all computers, I have to hit the "Esc" key twice to make the menu bar active, then hit the space bar to make the plane respond.
Planes and Drones work well but if you select any helicopter the system crashes and needs to be restarted, also many features within the program do not work, such as, when you move the mouse over the left side of the screen when running RF9 with a discrete graphics card, the aircraft and airport selection icons appear, but running with the Intel built in IGPU adapter the icons do not appear and you have to use the main menu bar to select a different model.
The graphics displayed with the Intel IGPU are not very good, see the attached picture, notice the awful black lines/patches in the grass.